February/March 2026 Paper 12

2026 · 40 questions · 40 parts · 40 marks

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26Dna Structure ReplicationHard1 mark
The scientist Erwin Chargaff analysed the base composition of the DNA of several species. The table shows some of Chargaff’s data.
percentage of base in DNA
speciesadenineguaninecytosinethymine
E.coli24.726.025.723.6
maize26.822.823.227.2
grasshopper29.320.520.729.3
sea urchin32.817.717.332.1
octopus33.217.617.631.6
rat28.621.420.528.4
Which statements can be concluded using only the data in the table?
  1. 1
    Cytosine binds to guanine using three hydrogen bonds.
  2. 2
    Approximately 50% of the bases in any of the species are either adenine or thymine.
  3. 3
    The base composition of DNA varies between different species.
  4. 4
    The number of cytosine bases in any of the species is approximately the same as the number of guanine bases.