May/June 2026 Paper 21

2026 · 6 questions · 27 parts · 60 marks

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1(a)(i)Microscopy MagnificationMedium2 marks
Figure 1.1 is a transmission electron micrograph of a section through part of the pancreas of a mammal.
Figure 1.1, a transmission electron micrograph of a section through part of the pancreas of a mammal at a magnification of ×5000, the cytoplasm filled with whorled stacks of rough endoplasmic reticulum, with organelle A (an elongated mitochondrion nested among the rough endoplasmic reticulum) and organelle B (a secretory vesicle/zymogen granule, one of many such granules clustered above) labelled
Describe the steps to determine the actual length in micrometres () of the organelle labelled A in Figure 1.1.

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1(a)(ii)Microscopy MagnificationEasy1 mark
The structures labelled A and B are visible when the cells in Figure 1.1 are viewed using a light microscope. State two other structures in the cells shown in Figure 1.1 that are visible when using a light microscope.

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1(a)(iii)Microscopy MagnificationMedium2 marks
Explain why some of the cell structures that are visible with the transmission electron microscope are not visible when using the light microscope.

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1(b)Cell Structure OrganellesMedium3 marks
The main function of the cells shown in Figure 1.1 is to synthesise and release enzymes that digest proteins, lipids and carbohydrates in the digestive system. State the cell structures visible in Figure 1.1 that are involved with the synthesis and release of enzymes and outline the role of each structure in these processes.

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